Buffett disciple Guy Spier’s rare cancer changed what he values most

Summary

Guy Spier, a value investor who had lunch with Warren Buffett, discusses his glioblastoma diagnosis and decision to close his hedge fund in 2026. He reflects on what truly matters in life, emphasizing love, gratitude, and living in the present. The conversation touches on his personal journey with cancer and the rare disease community.

• Guy Spier reveals he was diagnosed with glioblastoma grade 4 brain cancer.
• He closed his investment fund and returned money to investors in early 2026.
• Spier discusses the emotional impact of his diagnosis and his shift in priorities.
• He talks about his experimental treatments, including photodynamic therapy and a personalized vaccine.
• Spier emphasizes the importance of a positive mental attitude and daily movement.
• He shares his perspective on value investing and how his time horizon has shortened.
• The conversation explores the challenges of rare diseases and the need for more funding.
• Spier and host Becky Quick connect over their personal experiences with rare diseases.