Tips on the best time to close credit spreads

For those who trade a lot of short dated credit spreads or just have experience in general... How often do you find (0-1dte) vertical credit spreads exceeding 200-400%+ in value before eventually expiring worthless or rather.. at what point or percentage loss relative to the credit received do you believe most spreads are not worth holding onto. For example.. If the vertical spread in question has a 8:1 risk to reward ratio and intraday you're already down 7x the credit received, the odds of that spread closing otm are probably very low compared to closing when you're only down 1x the credit received but then you may lose out on potential wins closing so early. I also understand that this question is exceptionally broad... Since it's incredibly dependent on the deltas sold at and what credit you're receiving since some spreads could have a 2:1 or 8:1 risk to reward so to narrow this down a little, I'm referring to very far otm.. Sub 10 delta vertical spreads on spx, with a 6:1 to 9:1 risk to reward. So collecting .50-.70 cents. At what pnl loss relative to the credit received would you abandon the trade or do you instead watch for key levels to break or complete invalidation of the trade to begin with instead of pnl primarily? Curious on your guys thoughts Edit: For context, I usually close prior to 2pm (hate the gamma during and prior to power hour) for a 2x loss relative to credit received. I used to close sooner for a 1x loss but found myself closing too many winning trades so switched to 2x... And found the larger losses offsetting the extra winners to the point that my overall pnl difference from closing sooner didn't make a difference. It's profitable.. but just curious if there is a more optimal exit.