OKLO and NVIDIA Collaborate to Advance Nuclear Fuel Validation at Los Alamos in Support of Nuclear-Powered AI Factories

The partnership aims to advance critical nuclear infrastructure, artificial intelligence (AI)-enabled research, and nuclear fuel R&D to accelerate the deployment of nuclear energy and support "nuclear-powered AI factories." **Key Goals and Capabilities** The collaboration brings together Oklo's advanced sodium-fast-reactor platform, NVIDIA's AI infrastructure and high-performance computing, and LANL's world-leading expertise in materials science and nuclear fuels. According to Oklo CEO Jacob DeWitte, this partnership will specifically help advance Oklo's plutonium-bearing fuel work on its "Pluto" reactor (which is part of the Department of Energy's Reactor Pilot Program) and lay the groundwork for high-assurance, resilient power to support the federal government’s Genesis Mission. **Initial Focus Areas** The collaboration will initially concentrate on three main projects: 1. **AI for Fuel Validation**: Developing physics- and chemistry-based AI inference models to support research, development, and validation for plutonium-bearing nuclear fuels. 2. **Materials Science**: Conducting R&D around the fabrication of plutonium-bearing fuels. 3. **Nuclear-Powered AI Factories**: Studying power generation, grid reliability, redundancy, and stabilization to support the deployment of nuclear-powered AI data centers and factories at LANL. Ultimately, the agreement intends to combine advanced nuclear power, AI, digital twins, modeling, and simulation to drive critical infrastructure development for the next generation of mission-critical energy. https://oklo.com/newsroom/news-details/2026/Oklo-NVIDIA-and-Los-Alamos-National-Laboratory-Collaborate-to-Advance-Nuclear-Fuel-Validation-at-Los-Alamos-in-Support-of-Nuclear-Powered-AI-Factories/default.aspx