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Oklo announced today that it has signed a U.S. Department of Energy (DOE) Other Transaction Agreement (OTA) to support the design, construction, and operation of a radioisotope pilot plant (“Radioisotope Pilot Facility”) under the DOE Reactor Pilot Program (RPP). Signing the OTA is a major milestone which marks the transition from project selection and planning into active execution under DOE authorization.
“This OTA establishes a framework for execution and risk reduction. By building and operating a pilot reactor, we generate the data and experience to streamline future commercial deployments, improve regulatory efficiency, and deliver long-term value,” said Jacob DeWitte, co-founder and CEO of Oklo.
Atomic Alchemy Inc., an Oklo subsidiary, is using the Radioisotope Pilot Facility to lay the groundwork for future commercial plants that make medical and research radioisotopes in the United States. These radioisotopes are essential for diagnosing cancer, treating disease, powering medical research, and supporting national security. Today, many are produced overseas or in aging facilities. By first operating a pilot plant, Oklo can then scale into reliable, domestic production that helps ensure hospitals, researchers, and patients have consistent access to these lifesaving materials.
With the OTA now in place, Atomic Alchemy will focus its near-term resources on building the Radioisotope Pilot Facility under DOE authorization. As part of this learn-first-then-scale strategy, Atomic Alchemy has withdrawn its previously submitted Nuclear Regulatory Commission construction permit application for the Meitner-1 commercial radioisotope production facility at Idaho National Laboratory to focus on the Radioisotope Pilot Facility.
Oklo views the RPP as an enabler and accelerator to deliver advanced nuclear technologies that strengthen U.S. energy security, healthcare infrastructure, and industrial leadership.
https://www.businesswire.com/news/home/20260107011601/en/Oklo-and-DOE-Partner-to-Deploy-Radioisotope-Pilot-Facility-Supporting-Cancer-Care-and-U.S.-Medical-Supply-Chains