Calls
2
Roelof Botha
Managing Partner, Sequoia Capital
Win Rate
100.0%
return
+72.0%
Ticker
Side
Mentions
First Call
Call Price
P&L
Thesis
Theme
Source
Long
Apr 02
$58.00
+32.0%
Roelof says Block's board quickly and fully supported Jack's AI-driven restructuring because Jack laid out the logic in a principled, detailed, non-reactionary memo. Management engaged with feedback rather than being dogmatic, and the board-management trust was strong enough to make a crucial decision quickly. This governance and execution de-risks Block's transformation.
Payments & Fintech
Long
Oct 09
$173.29
+111.9%
Natera, which Sequoia seeded with $1 million in 2007, has grown into a roughly $22 billion market-cap company and is today the leading provider of prenatal testing, oncology recurrence monitoring and organ-transplant rejection testing. Botha calls it a huge success and frames genetic diagnostics as an area that is still collecting the dividend of the Human Genome Project from 25 years ago, the one corner of life sciences where Sequoia's bet has clearly worked.
Diagnostics
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Roelof Botha has 2 trade ideas tracked on Buzzberg across 2 tickers since October 2025. Most covered: NTRA, SQ.
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