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A FY2025 Q4 IMPROVING

Agilent Technologies, Inc. earnings call

Nov 24, 2025 · 16:30 ET Adam ElanoffAngelica RymanMike Zhang
Buzzberg read

FY26 core growth guided to 4-6% with 75bps margin expansion

Agilent reported strong Q4 FY25 results with 7.2% core growth and above-consensus EPS, citing robust demand in pharma (12% growth) and CDMO (40%+ growth). Management guided to a prudent FY26 with 4-6% core revenue growth and 75bps margin expansion, while navigating tariff headwinds, a higher tax rate, and an accelerating replacement cycle. The company highlighted its IGNITE operating system and new product launches as key drivers of share gains. Q4 FY25 revenue of $1.86B grew 7.2% core, beating guidance, with all major end markets showing growth except academia & government.

Buzzberg read FY26 core growth guided to 4-6% with 75bps margin expansion Agilent reported strong Q4 FY25 results with 7.2% core growth and above-consensus EPS, citing robust demand in pharma (12% growth) and CDMO (40%+ growth). Management guided to a prudent FY26 with 4-6% core revenue growth and 75bps margin expansion, while navigating tariff headwinds, a higher tax rate, and an accelerating replacement cycle. The company highlighted its IGNITE operating system and new product launches as key drivers of share gains. Q4 FY25 revenue of $1.86B grew 7.2% core, beating guidance, with all major end markets showing growth except academia & government. Read full analysisCollapse analysis

Agilent reported strong Q4 FY25 results with 7.2% core growth and above-consensus EPS, citing robust demand in pharma (12% growth) and CDMO (40%+ growth). Management guided to a prudent FY26 with 4-6% core revenue growth and 75bps margin expansion, while navigating tariff headwinds, a higher tax rate, and an accelerating replacement cycle. The company highlighted its IGNITE operating system and new product launches as key drivers of share gains. Q4 FY25 revenue of $1.86B grew 7.2% core, beating guidance, with all major end markets showing growth except academia & government.

  • CDMO (BioVectra) grew over 40% core, driven by GLP-1 and SI RNA demand, with a nearly full order book for FY26.
  • New products (Infinity Tree, ProIQ LCMS, Alturo column) are driving significant share gains, notably 50%+ growth in single-quad LCMS.
  • FY26 guidance calls for 4-6% core revenue growth, 75bps op margin expansion, and 5-7% EPS growth, despite a 250bps tax rate headwind.
Revenue $1.861B reported
EPS $1.59 reported
Gross margin 51.8% reported
Op margin 23.8% reported

What changed this quarter

01
Guidance

FY26 core growth guided to 4-6% with 75bps margin expansion

Guidance · revenue to $7.35B

02
Tariffs

Tariffs fully mitigated in FY26 through task force actions

Q4 FY25 revenue of $1.86B grew 7.2% core, beating guidance, with all major end markets showing growth except academia & government.

03
Demand

CDMO orders robust, capacity expansion on track for 2027

Management emphasized strong execution, broad-based momentum, and a robust pipeline of innovation, while framing FY26 guidance as prudent but positioned for above-peer growth.

04
Product Innovation

ProIQ LCMS drives 50%+ single-quad growth in Q4

New products (Infinity Tree, ProIQ LCMS, Alturo column) are driving significant share gains, notably 50%+ growth in single-quad LCMS.

AI, capex & demand read

AI

Platform & monetization

Management discussed using AI internally to accelerate innovation and operations, such as AI generating 80% of engineering drawings and reducing custom design cycle times by 75%, and agentic AI in order fulfillment to reduce downtime and improve quality. They are also planning to deploy AI in CRM and virtual agents to enhance customer intimacy, but did not discuss AI as a product or revenue driver

Demand

Bookings & conversion

CDMO orders robust, capacity expansion on track for 2027. Management emphasized strong execution, broad-based momentum, and a robust pipeline of innovation, while framing FY26 guidance as prudent but positioned for above-peer growth.

Capex

Investment and capacity

Management raised capital expenditures by $100 million to $500 million for FY26, primarily for incremental NASD (CDMO) capacity and consumable expansion, with new capacity expected to go live in early-to-mid 2027.

Tone · Confident

Management emphasized strong execution, broad-based momentum, and a robust pipeline of innovation, while framing FY26 guidance as prudent but positioned for above-peer growth.

Supply-chain alpha

A1

Agilent's new CTO from Thermo Fisher (TMO) and manufacturing leader from Gilead (GILD) signal a strategic push to bolster R&D and operational efficiency. This could intensify competition in the analytical instruments space.

“August Specht, who joined us from Thermo Fisher as our Chief Technology Officer, brings deep scientific knowledge in analytical technologies”
Parikh McDonald
A2

Agilent's management states pharma reshoring is a significant opportunity, estimating a $1 billion addressable market by 2030. They are in early conversations and expect orders by end of 2026, but this is a long-term, multi-year tailwind.

“We expect by the end of 26 that we'll get some orders in that area. So we're estimating the opportunity of about $1 billion by 2030”
Parikh McDonald
A3

Agilent's BioVectra CDMO business is driving significant growth, and management has noted robust booking for FY26, with orders largely covering the full year. This signals strong demand for contract peptide manufacturing, particularly for GLP-1s.

“we've got a very robust order book as we enter the year for pretty much the full year”
Simon May
A4

In Q4, Agilent's 'single-quad LCMS' (ProIQ launch) grew more than 50%, and the Alturo BioInert column ramp is 'an order of magnitude greater' than past launches. This suggests Agilent is winning significant share in the high-growth GLP-1 and oligonucleotide analytical workflow segment.

“The summer launch of our ProIQ drove overall single-quad LCMS growth of more than 50% in the first full quarter.”
Parikh McDonald

Forward guidance

ImprovingGuidance · revenue to $7.35B
Forward guidance
MetricPeriodRangeMidpointStatus
CapexFY2026500500GUIDED
EPSFY2026$5.86–$6.00$5.93GUIDED
EPSFY2026 Q1$1.35–$1.38$1.36GUIDED
Free cash flowFY2026$1.6B–$1.7B$1.65BGUIDED
Op marginFY20260.75%0.75%GUIDED
RevenueFY2026$7.3B–$7.4B$7.35BGUIDED
RevenueFY2026 Q1$1.79B–$1.82B$1.805BGUIDED

Guidance credibility

2 / 2met or beat
Guidance credibility
IssuedMetricTargetGuideActualOutcome
FY2026 Q1EPSFY2026 Q2$1.39–$1.42$1.49Met / beat
FY2026 Q1RevenueFY2026 Q2$1.79B–$1.82B$1.835BMet / beat

Company read-throughs

+25.1%
since call
$334.30$418.18
Supply chain

Agilent's new CFO comes from Amgen, bringing Big Pharma finance experience. This is a talent move rather than a business signal for Amgen.

“Adam joins us after distinguished tenure at Amgen.”
Parikh McDonald
+9.5%
since call
$125.27$137.14
Supply chainSupply-chain alpha

Agilent's new CTO from Thermo Fisher (TMO) and manufacturing leader from Gilead (GILD) signal a strategic push to bolster R&D and operational efficiency. This could intensify competition in the analytical instruments space. — Leadership hires from a direct competitor and a major pharma customer indicate Agilent is planning for a more aggressive, innovation-led growth phase.

“Jaydeep Ganguly joined from Gilead to drive world-class manufacturing”
Parikh McDonald
+3.1%
since call
$584.50$602.51
Supply chainSupply-chain alpha

In Q4, Agilent's 'single-quad LCMS' (ProIQ launch) grew more than 50%, and the Alturo BioInert column ramp is 'an order of magnitude greater' than past launches. This suggests Agilent is winning significant share in the high-growth GLP-1 and oligonucleotide analytical workflow segment. — These are high-value, high-margin consumables and instruments; rapid adoption indicates a potential durable share shift in a critical market segment, pressuring competitors.

“August Specht, who joined us from Thermo Fisher as our Chief Technology Officer”
Parikh McDonald
+3.1%
since call
$584.50$602.51
Supply chainSupply-chain alpha

Agilent's management states pharma reshoring is a significant opportunity, estimating a $1 billion addressable market by 2030. They are in early conversations and expect orders by end of 2026, but this is a long-term, multi-year tailwind.