She's the youngest woman to have led a Fortune 500 company and now runs a $100B+ healthcare giant
Watch on YouTube ↗  |  February 17, 2026 at 11:39 UTC  |  45:59  |  CNBC
Speakers
Sarah London — CEO of Centene Corporation

Summary

  • Centene is executing a strategic pivot from "growth at all costs" to focusing on margin expansion and industry-leading cost structures.
  • The company aims to automate the entire back-end of the business (claims processing) with a goal of "zero human intervention," leveraging AI to eliminate billions in administrative waste.
  • The healthcare industry faces significant headwinds in 2024/2025 due to policy shifts and cost pressures, particularly in government-sponsored programs (Medicaid/Medicare).
  • Management views the mission of serving underserved populations as aligned with profitability: better health outcomes lower total costs, preserving taxpayer dollars and increasing margins.
Trade Ideas
Ticker Direction Speaker Thesis Time
CNC
LONG Sarah London
CEO of Centene Corporation
"We are not just focused on growth like we have been in the past... we want to deliver industry leading outcomes at an industry leading cost structure." She also notes the goal to "run the entire back end of our business digitally in an automated fashion with the goal of zero human intervention." Centene is transitioning from a volume-based aggregator to a margin-focused operator. By utilizing AI to automate claims and administrative tasks ("the unsexy part"), they can drastically reduce SG&A expenses. In the insurance business, flat revenue with significantly lower administrative costs results in substantial free cash flow expansion and earnings growth. LONG. The operational turnaround and aggressive cost-cutting via technology provide a clear path to value creation, even amidst a challenging policy environment. Policy shifts in Medicaid reimbursement rates, execution risk on the digital transformation, and potential regulatory scrutiny on AI-driven claims processing.
WATCH Sarah London
CEO of Centene Corporation
She calls 2025 "an incredibly challenging year for the industry as policy shifts and cost pressures reshape the American health care system." While the long-term thesis for efficiency is strong, the immediate macro environment for managed care is hostile due to government policy changes (likely referring to Medicaid redeterminations and Medicare Advantage rate pressures). This suggests near-term volatility for the broader sector before the efficiency gains materialize. WATCH. Wait for policy clarity before aggressive sector-wide allocation, though individual turnaround stories (like CNC) may outperform. adverse government rate setting, higher-than-expected medical utilization trends. 0:13